Written by Ana Kormos, University of California Irvine Malaria Initiative

The University of California Irvine Malaria Initiative (UCIMI) is a not-for-profit research collaborative whose mission is to contribute to the eradication of human malaria.

UCIMI has developed gene drive-based systems for the modification of the African malaria vector mosquito, Anopheles gambiae, to prevent them from transmitting the parasites that cause malaria.

Our population modification strategy (also known as population replacement) is designed to rapidly spread beneficial genes that prevent malaria parasite transmission by the mosquito throughout the vector population. This strategy eliminates the parasite, not the mosquito, which we believe has many advantages over strategies aimed at reducing or suppressing mosquito populations.