{"id":4217,"date":"2026-04-20T06:53:47","date_gmt":"2026-04-20T06:53:47","guid":{"rendered":"https:\/\/genedrivenetwork.org\/?p=4217"},"modified":"2026-04-20T10:42:46","modified_gmt":"2026-04-20T10:42:46","slug":"local-leadership-global-partnerships-placing-african-scientists-at-the-forefront-of-the-fight-to-end-malaria","status":"publish","type":"post","link":"https:\/\/genedrivenetwork.org\/fr\/blog\/local-leadership-global-partnerships-placing-african-scientists-at-the-forefront-of-the-fight-to-end-malaria\/","title":{"rendered":"Local leadership, global partnerships: Placing African scientists at the forefront of the fight to end malaria"},"content":{"rendered":"<p>As the Outreach Network for Gene Drive Research marks <a href=\"https:\/\/www.who.int\/campaigns\/world-malaria-day\/2026\">World Malaria Day<\/a> under the theme \u201cLocal Leadership, Global Partnerships: Together Against Malaria\u201d, we are reminded that malaria remains one of the world\u2019s most widespread infectious diseases. Despite decades of efforts, the disease continues to claim hundreds of thousands of lives each year, most of them in sub\u2011Saharan Africa.<\/p>\n\n\n\n<p>In 2024, there were an estimated\u00a0<a href=\"https:\/\/www.who.int\/teams\/global-malaria-programme\/reports\/world-malaria-report-2025\">282 million malaria cases and 610\u202f000 deaths worldwide<\/a>, with the WHO African Region alone accounting for\u00a0about 95% of global cases and deaths, most of which are children under the age of five. Mali, where the <a href=\"https:\/\/acemeafrica.com\/\">African Center for Excellence in Molecular Engineering (ACEME)<\/a> is based, is among 11 African countries that together account for around two\u2011thirds of global malaria cases and deaths.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1280\" height=\"884\" src=\"https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/res-bill-wegener-LqOO5Ko0zSo-unsplash-1.jpg\" alt=\"\" class=\"wp-image-4219\" srcset=\"https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/res-bill-wegener-LqOO5Ko0zSo-unsplash-1.jpg 1280w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/res-bill-wegener-LqOO5Ko0zSo-unsplash-1-1043x720.jpg 1043w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/res-bill-wegener-LqOO5Ko0zSo-unsplash-1-768x530.jpg 768w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/res-bill-wegener-LqOO5Ko0zSo-unsplash-1-18x12.jpg 18w\" sizes=\"auto, (max-width: 1280px) 100vw, 1280px\" \/><\/figure>\n\n\n\n<p>In the face of mounting challenges \u2013 from growing resistance to existing tools and funding shortfalls, to shifting transmission patterns driven by climate change \u2013 we need to continually&nbsp;adapt&nbsp;our response to malaria and work to develop new interventions.<\/p>\n\n\n\n<p>Genetic approaches to vector control are a promising innovation being explored, which has the potential to work alongside existing interventions to help reduce transmission of malaria and other vector-borne diseases. To date though, a consistent share of the research and development of these innovative tools has taken place outside of African institutions, despite the continent bearing the biggest disease burden. ACEME was created in this context: to establish a research center and training platform able to place African scientists at the forefront of developing innovative approaches to fight vector-borne diseases, such as malaria.<\/p>\n\n\n\n<p><strong>Establishing our Center for Excellence in Bamako, Mali<\/strong> <\/p>\n\n\n\n<p>ACEME aims to address a regional need for advanced technical expertise and infrastructural capacity in molecular engineering. Our team, based at the <a href=\"http:\/\/www.usttb.edu.ml\/\">University of Sciences, Techniques and Technologies of Bamako (USTTB)<\/a>, is working to establish a research and training platform to support global efforts to develop innovative approaches for vector control. The center will provide a setting for African scientists to learn and develop advanced skills in genetic engineering, including those linked to the development of genetically modified mosquitoes. Over the coming years, we aim to become a place where African researchers can gain the knowledge and experience needed to lead the development of new approaches for vector control from within the African region.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1620\" height=\"1080\" src=\"https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/DSC00760-1620x1080.jpg\" alt=\"\" class=\"wp-image-4220\" srcset=\"https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/DSC00760-1620x1080.jpg 1620w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/DSC00760-1080x720.jpg 1080w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/DSC00760-768x512.jpg 768w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/DSC00760-1536x1024.jpg 1536w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/DSC00760-2048x1365.jpg 2048w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/DSC00760-18x12.jpg 18w\" sizes=\"auto, (max-width: 1620px) 100vw, 1620px\" \/><\/figure>\n\n\n\n<p class=\"has-accent-color has-text-color has-link-color wp-elements-c83354aa5970d869496d2c8a3060bffc\" style=\"font-size:16px\"><em>Researcher working in the laboratory at the University of Sciences, Techniques and Technologies in Bamako, Mali. Photograph: ACEME\u00a0 <\/em><\/p>\n\n\n\n<p>Our laboratory at the University of Sciences, Techniques and Technologies (USTTB) in Bamako has been set up to meet Arthropod Containment Level 2 (ACL2) standards, a demanding certification that guarantees our compliance with international standards for work in containment with genetically modified organisms.&nbsp;The facility is also equipped with state-of-the-art instrumentation and molecular tools, enabling high\u2011quality research and supporting the long\u2011term development of local capacity in molecular engineering.<\/p>\n\n\n\n<p><strong>From Bamako to Keele and back<\/strong><\/p>\n\n\n\n<p>In preparation for the launch of our center, we have also been working to strengthen our local team\u2019s expertise. Through a capacity\u2011building partnership with&nbsp;<a href=\"https:\/\/www.keele.ac.uk\/\" target=\"_blank\" rel=\"noreferrer noopener\">Keele University<\/a>&nbsp;in the United Kingdom, we have been strengthening our skills in vector biology and molecular genetics and laying the foundations for a training offer that we hope will eventually benefit researchers from across the African region. As part of this collaboration, members of our team have been receiving hands\u2011on training in genetic engineering techniques, including the design and testing of genetic constructs and the development of genetically modified mosquitoes as potential tools for vector control.<br><\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1280\" height=\"853\" src=\"https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/resDSC01011.jpg\" alt=\"\" class=\"wp-image-4221\" srcset=\"https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/resDSC01011.jpg 1280w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/resDSC01011-1080x720.jpg 1080w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/resDSC01011-768x512.jpg 768w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/resDSC01011-18x12.jpg 18w\" sizes=\"auto, (max-width: 1280px) 100vw, 1280px\" \/><\/figure>\n\n\n\n<p class=\"has-accent-color has-text-color has-link-color wp-elements-01e8dba20d152684ec56b7ec47b5664e\" style=\"font-size:16px\"><em>Researchers at work in the laboratory at the University of Sciences, Techniques and Technologies in Bamako, Mali. Photograph: ACEME<\/em>\u00a0<\/p>\n\n\n\n<p>In 2024, following approval from the relevant authorities, we\u00a0<a href=\"https:\/\/acemeafrica.com\/building-capacity-to-fight-mosquito-borne-diseases\/\" target=\"_blank\" rel=\"noreferrer noopener\">imported<\/a>\u00a0a non\u2011genetically modified laboratory strain of mosquitoes called \u201cG3\u201d from Keele University and began working with it in an insectary designed to meet international and national containment standards. The ACEME team independently designed and assembled molecular constructs carrying fluorescent markers and is currently inserting them into the genome of the mosquitoes. All activities are being conducted entirely within the ACL2\u2011compliant laboratory at USTTB and are focused on building the technical expertise, operational systems, and research culture that will underpin future studies and training programmes in genetic approaches for vector\u2011borne disease control.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1280\" height=\"853\" src=\"https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/DSC0B0061.jpg\" alt=\"\" class=\"wp-image-4222\" srcset=\"https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/DSC0B0061.jpg 1280w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/DSC0B0061-1080x720.jpg 1080w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/DSC0B0061-768x512.jpg 768w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2026\/04\/DSC0B0061-18x12.jpg 18w\" sizes=\"auto, (max-width: 1280px) 100vw, 1280px\" \/><\/figure>\n\n\n\n<p class=\"has-accent-color has-text-color has-link-color wp-elements-0b5799b265d786d58c44049d66cdb46c\" style=\"font-size:16px\"><em>Researchers from the ACEME team receive the strain of \u201cG3\u201d mosquitoes from Keele University.\u00a0Photograph: ACEME<\/em><\/p>\n\n\n\n<p>Lakamy Sylla, co-investigator at ACEME, is pursuing a PhD in entomology at Keele University focused on the genetic manipulation of reproductive genes in&nbsp;<em>Anopheles gambiae<\/em>, one of the main malaria vectors in sub\u2011Saharan Africa. This involves combining computational design of genetic constructs with laboratory experiments in the UK and Bamako and feeding the lessons learned back into ACEME\u2019s work. Most members of our core scientific team are also undertaking PhDs or other advanced training, and as ACEME grows we plan to expand this cohort and host visiting researchers and short courses for colleagues from across the continent.<\/p>\n\n\n\n<p><strong>Connecting research, policy and communities<\/strong><\/p>\n\n\n\n<p>Malaria and other vector\u2011borne diseases in Africa cut across sectors: they affect health systems, education, livelihoods and the environment. Addressing them requires coordination between researchers, public health authorities, regulators, communities and international partners.<\/p>\n\n\n\n<p>Centers like ACEME contribute to this collaborative effort by strengthening skills, infrastructure and networks around the development of new approaches to fight vector-borne diseases. As well as sharing information about our work with Mali\u2019s National Malaria Control Program, regulatory authorities and civil society organizations, we take part in <a href=\"https:\/\/acemeafrica.com\/21st-rbm-vcwg-annual-workshop\/\">regional<\/a> and <a href=\"https:\/\/acemeafrica.com\/2025-gordon-2025-gordon-research-conference\/\">global<\/a> discussions on vector\u2011borne diseases and genetic biocontrol, helping to bring African research perspectives into debates on how future tools might fit within national and continental strategies.<\/p>\n\n\n\n<p>By investing in African scientists, strengthening partnerships and showing up in spaces for discussion across the continent and beyond, ACEME is working to ensure that future malaria tools are researched and developed with African priorities at their core.<\/p>","protected":false},"excerpt":{"rendered":"<p>As the Outreach Network for Gene Drive Research marks World Malaria Day under the theme \u201cLocal Leadership, Global Partnerships: Together Against Malaria\u201d, we are reminded that malaria remains one of the world\u2019s most widespread infectious diseases. Despite decades of efforts, the disease continues to claim hundreds of thousands of lives each year, most of them&hellip;<\/p>","protected":false},"author":69,"featured_media":4220,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[816],"tags":[],"post_series":[],"class_list":["post-4217","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","entry","has-media"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Local leadership, global partnerships: Placing African scientists at the forefront of the fight to end malaria - Gene Drive Network<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/genedrivenetwork.org\/fr\/blog\/local-leadership-global-partnerships-placing-african-scientists-at-the-forefront-of-the-fight-to-end-malaria\/\" \/>\n<meta property=\"og:locale\" content=\"fr_CA\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Local leadership, global partnerships: Placing African scientists at the forefront of the fight to end malaria - Gene Drive Network\" \/>\n<meta property=\"og:description\" content=\"As the Outreach Network for Gene Drive Research marks World Malaria Day under the theme \u201cLocal Leadership, Global Partnerships: Together Against Malaria\u201d, we are reminded that malaria remains one of the world\u2019s most widespread infectious diseases. 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