{"id":3380,"date":"2024-12-13T16:11:15","date_gmt":"2024-12-13T16:11:15","guid":{"rendered":"https:\/\/genedrivenetwork.org\/?p=3380"},"modified":"2024-12-13T16:11:25","modified_gmt":"2024-12-13T16:11:25","slug":"mapping-the-malaria-vector-anopheles-coluzzii-in-sao-tome-and-principe","status":"publish","type":"post","link":"https:\/\/genedrivenetwork.org\/fr\/blog\/mapping-the-malaria-vector-anopheles-coluzzii-in-sao-tome-and-principe\/","title":{"rendered":"Mapping the malaria vector Anopheles coluzzii in S\u00e3o Tom\u00e9 and Pr\u00edncipe"},"content":{"rendered":"<p>Among the species of mosquitoes that transmit malaria, <em>Anopheles coluzzii<\/em> stands out for its resilience and adaptability. Found primarily across West Africa, this species is the only malaria-transmitting mosquito present on the islands of S\u00e3o Tom\u00e9 and Pr\u00edncipe, making it a focal point for our work at the University of California Malaria Initiative (<a href=\"https:\/\/stopmalaria.org\/\" target=\"_blank\" rel=\"noreferrer noopener\">UCMI<\/a>).\u00a0<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1280\" height=\"960\" src=\"https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2024\/12\/resfield.jpg\" alt=\"\" class=\"wp-image-3383\" srcset=\"https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2024\/12\/resfield.jpg 1280w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2024\/12\/resfield-960x720.jpg 960w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2024\/12\/resfield-768x576.jpg 768w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2024\/12\/resfield-16x12.jpg 16w\" sizes=\"auto, (max-width: 1280px) 100vw, 1280px\" \/><\/figure>\n\n\n\n<p class=\"has-accent-color has-text-color has-link-color wp-elements-6ad4c556ca5b3f61c7def753b70f6e42\" style=\"font-size:16px\"><em>UCMI\u2019s team conducting field activities in S\u00e3o Tom\u00e9 and Pr\u00edncipe.\u00a0<\/em>Photograph: UCMI<\/p>\n\n\n\n<p>At UCMI, we are working towards malaria elimination by developing genetic technologies to modify mosquitoes to prevent malaria transmission.&nbsp;In a recent&nbsp;<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11589655\/pdf\/EVA-17-e70044.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">publication<\/a>,&nbsp;we looked at the genetics of <em>A. coluzzii<\/em> mosquitoes on the islands of S\u00e3o Tom\u00e9 and Pr\u00edncipe, offering insights into the local mosquito population composition and their movement.<\/p>\n\n\n\n<p>Sampling the full geographic range of the species on both islands, we used two different approaches to estimate the mosquitoes\u2019 dispersal: spatial autocorrelation and convolutional neural network models. Our findings? Mosquitoes on the islands seem to travel up to 3 and 7 kilometers, depending on the method of analysis. This difference underscores the complexity of mosquito movement and the value of using multiple approaches to gain a comprehensive understanding of dispersal dynamics. Overall, we found little genetic variation within mosquito populations, suggesting that <em>A. coluzzii<\/em> mosquitoes exist as a single Mendelian population on each island.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1280\" height=\"854\" src=\"https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2024\/12\/resField-Principe-2019.jpg\" alt=\"\" class=\"wp-image-3384\" srcset=\"https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2024\/12\/resField-Principe-2019.jpg 1280w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2024\/12\/resField-Principe-2019-1079x720.jpg 1079w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2024\/12\/resField-Principe-2019-768x512.jpg 768w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2024\/12\/resField-Principe-2019-18x12.jpg 18w\" sizes=\"auto, (max-width: 1280px) 100vw, 1280px\" \/><\/figure>\n\n\n\n<p class=\"has-accent-color has-text-color has-link-color wp-elements-6ad4c556ca5b3f61c7def753b70f6e42\" style=\"font-size:16px\"><em>UCMI\u2019s team conducting field activities in S\u00e3o Tom\u00e9 and Pr\u00edncipe.\u00a0<\/em>Photograph: UCMI<\/p>\n\n\n\n<p>These findings suggest that a gene drive could spread efficiently within these mosquito populations, making the islands a promising site for potential future field evaluations of gene drive mosquitoes. This research represents an important step in the development of gene drive technologies as a tool to fight malaria. Our hope is that it will help inform future work on gene drive mosquitoes and contribute to the development of mathematical models to predict mosquito populations dynamics.<\/p>\n\n\n\n<p>Read the full study <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11589655\/pdf\/EVA-17-e70044.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">here<\/a>. \u00a0<\/p>\n\n\n\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>Among the species of mosquitoes that transmit malaria, Anopheles coluzzii stands out for its resilience and adaptability. Found primarily across West Africa, this species is the only malaria-transmitting mosquito present on the islands of S\u00e3o Tom\u00e9 and Pr\u00edncipe, making it a focal point for our work at the University of California Malaria Initiative (UCMI).\u00a0 UCMI\u2019s&hellip;<\/p>","protected":false},"author":41,"featured_media":3383,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[816],"tags":[],"post_series":[],"class_list":["post-3380","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","entry","has-media"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Mapping the malaria vector Anopheles coluzzii in S\u00e3o Tom\u00e9 and Pr\u00edncipe - Gene Drive Network<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/genedrivenetwork.org\/fr\/blog\/mapping-the-malaria-vector-anopheles-coluzzii-in-sao-tome-and-principe\/\" \/>\n<meta property=\"og:locale\" content=\"fr_CA\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mapping the malaria vector Anopheles coluzzii in S\u00e3o Tom\u00e9 and Pr\u00edncipe - Gene Drive Network\" \/>\n<meta property=\"og:description\" content=\"Among the species of mosquitoes that transmit malaria, Anopheles coluzzii stands out for its resilience and adaptability. Found primarily across West Africa, this species is the only malaria-transmitting mosquito present on the islands of S\u00e3o Tom\u00e9 and Pr\u00edncipe, making it a focal point for our work at the University of California Malaria Initiative (UCMI).\u00a0 UCMI\u2019s&hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/genedrivenetwork.org\/fr\/blog\/mapping-the-malaria-vector-anopheles-coluzzii-in-sao-tome-and-principe\/\" \/>\n<meta property=\"og:site_name\" content=\"Gene Drive Network\" \/>\n<meta property=\"article:published_time\" content=\"2024-12-13T16:11:15+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-12-13T16:11:25+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2024\/12\/resfield.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"960\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Gregory Lanzaro and Melina Campos\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Gregory Lanzaro and Melina Campos\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimation du temps de lecture\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/genedrivenetwork.org\\\/es\\\/blog\\\/mapping-the-malaria-vector-anopheles-coluzzii-in-sao-tome-and-principe\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/genedrivenetwork.org\\\/es\\\/blog\\\/mapping-the-malaria-vector-anopheles-coluzzii-in-sao-tome-and-principe\\\/\"},\"author\":{\"name\":\"Gregory Lanzaro and Melina Campos\",\"@id\":\"https:\\\/\\\/yellow-elephant-938991.hostingersite.com\\\/#\\\/schema\\\/person\\\/383176e97632d0d4e0768f4a4cfd9fff\"},\"headline\":\"Mapping the malaria vector Anopheles coluzzii in S\u00e3o Tom\u00e9 and Pr\u00edncipe\",\"datePublished\":\"2024-12-13T16:11:15+00:00\",\"dateModified\":\"2024-12-13T16:11:25+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/genedrivenetwork.org\\\/es\\\/blog\\\/mapping-the-malaria-vector-anopheles-coluzzii-in-sao-tome-and-principe\\\/\"},\"wordCount\":328,\"publisher\":{\"@id\":\"https:\\\/\\\/yellow-elephant-938991.hostingersite.com\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/genedrivenetwork.org\\\/es\\\/blog\\\/mapping-the-malaria-vector-anopheles-coluzzii-in-sao-tome-and-principe\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/genedrivenetwork.org\\\/wp-content\\\/uploads\\\/2024\\\/12\\\/resfield.jpg\",\"articleSection\":[\"Blog\"],\"inLanguage\":\"fr-CA\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/genedrivenetwork.org\\\/es\\\/blog\\\/mapping-the-malaria-vector-anopheles-coluzzii-in-sao-tome-and-principe\\\/\",\"url\":\"https:\\\/\\\/genedrivenetwork.org\\\/es\\\/blog\\\/mapping-the-malaria-vector-anopheles-coluzzii-in-sao-tome-and-principe\\\/\",\"name\":\"Mapping the malaria vector Anopheles coluzzii in S\u00e3o Tom\u00e9 and Pr\u00edncipe - 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