{"id":1886,"date":"2022-04-29T12:00:44","date_gmt":"2022-04-29T12:00:44","guid":{"rendered":"https:\/\/genedrivenetwork.org\/blog\/gene-drive-technologies-could-significantly-improve-our-malaria-control-toolkit\/"},"modified":"2022-04-29T12:00:44","modified_gmt":"2022-04-29T12:00:44","slug":"gene-drive-technologies-could-significantly-improve-our-malaria-control-toolkit","status":"publish","type":"post","link":"https:\/\/genedrivenetwork.org\/fr\/blog\/gene-drive-technologies-could-significantly-improve-our-malaria-control-toolkit\/","title":{"rendered":"Gene drive technologies could significantly improve our malaria-control toolkit"},"content":{"rendered":"<p style=\"text-align: justify;\">A <a href=\"https:\/\/www.economist.com\/graphic-detail\/2022\/03\/19\/squashing-malaria-could-save-as-many-lives-as-covid-19-has-taken\">recent article<\/a> by <em>The Economist<\/em> provides an overview of recent vaccine advances in the fight against malaria. Oxford scientists have developed a jab that shows 77% effectiveness and hope to apply for pre-qualification from the World Health Organization (WHO) in the fall. If it goes well, the Oxford version will be another great scientific breakthrough, complementing the <a href=\"https:\/\/www.who.int\/news\/item\/06-10-2021-who-recommends-groundbreaking-malaria-vaccine-for-children-at-risk\">RTS,S malaria vaccine<\/a> that currently requires four doses and only reduces severe infections by 30%.<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-1850\" src=\"https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2022\/01\/mosquito-3f9.jpg\" width=\"800\" height=\"533\" caption=\"false\" srcset=\"https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2022\/01\/mosquito-3f9.jpg 1880w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2022\/01\/mosquito-3f9-1080x720.jpg 1080w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2022\/01\/mosquito-3f9-1620x1080.jpg 1620w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2022\/01\/mosquito-3f9-768x512.jpg 768w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2022\/01\/mosquito-3f9-1536x1024.jpg 1536w, https:\/\/genedrivenetwork.org\/wp-content\/uploads\/2022\/01\/mosquito-3f9-1200x800.jpg 1200w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/p>\n<p><!--more--><\/p>\n<p style=\"text-align: justify;\">Vaccines are undoubtedly an important tool against malaria, but they are not enough to eliminate the disease. Insecticide-impregnated bed nets and distributing antimalarial drugs, for example, can still reach more people. However, they also have limitations. According to the <a href=\"https:\/\/www.who.int\/publications\/i\/item\/9789240040496\">2021 World Malaria Report<\/a>, 78 countries reported mosquito resistance to at least 1 of the 4 commonly-used insecticide classes in the period 2010\u20132019. WHO also expressed concern about the increasing <a href=\"https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/malaria\">drug resistance<\/a> in the Greater Mekong subregion and on the African continent.<\/p>\n<p style=\"text-align: justify;\"><em>The Economist<\/em> highlights gene drive technologies as one of the potential tools needed to build a strong front against malaria in the upcoming decade. According to modelers at the <a href=\"https:\/\/www.lshtm.ac.uk\/\">London School of Hygiene and Tropical Medicine<\/a>, jointly using vaccines, gene editing and existing approaches \u2013 such as insecticide-treated bed nets or antimalarial drugs \u2013 could cut deaths caused by malaria by 75% in the next ten years. In other words, such novel tools could save up to 20 million lives from malaria by 2030, a number that the article estimates to equal the death toll of Covid-19 in the same time span, making a clear case for ongoing research and innovation in genetic modification for vector control.<\/p>\n<p style=\"text-align: justify;\">Gene drives also featured in <em>The Economist<\/em>\u2019s podcast on science and technology called Babbage. The <a href=\"https:\/\/www.economist.com\/podcasts\/2022\/04\/05\/how-do-you-solve-a-problem-like-malaria\">episode<\/a> includes an interview with Dr Federica Bernardini, Senior Postdoctoral Researcher for <a href=\"https:\/\/targetmalaria.org\/\">Target Malaria<\/a>, who offers a fascinating virtual tour of the Crisanti lab at Imperial College London. There, she shares some details of the project\u2019s ongoing research, which includes injecting mosquito embryos with a molecular component that can be integrated in their genome to render them sterile.<\/p>\n<p style=\"text-align: justify;\">Read the full article on <em>The Economist<\/em>\u2019s <a href=\"https:\/\/www.economist.com\/graphic-detail\/2022\/03\/19\/squashing-malaria-could-save-as-many-lives-as-covid-19-has-taken\">website<\/a>.<\/p>","protected":false},"excerpt":{"rendered":"<p>A recent article by The Economist provides an overview of recent vaccine advances in the fight against malaria. Oxford scientists have developed a jab that shows 77% effectiveness and hope to apply for pre-qualification from the World Health Organization (WHO) in the fall. If it goes well, the Oxford version will be another great scientific&hellip;<\/p>","protected":false},"author":1,"featured_media":1850,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[816],"tags":[],"post_series":[],"class_list":["post-1886","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","entry","has-media"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Gene drive technologies could significantly improve our malaria-control toolkit - Gene Drive Network<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/genedrivenetwork.org\/fr\/blog\/gene-drive-technologies-could-significantly-improve-our-malaria-control-toolkit\/\" \/>\n<meta property=\"og:locale\" content=\"fr_CA\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Gene drive technologies could significantly improve our malaria-control toolkit - Gene Drive Network\" \/>\n<meta property=\"og:description\" content=\"A recent article by The Economist provides an overview of recent vaccine advances in the fight against malaria. Oxford scientists have developed a jab that shows 77% effectiveness and hope to apply for pre-qualification from the World Health Organization (WHO) in the fall. 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