{"id":1648,"date":"2019-12-16T11:54:30","date_gmt":"2019-12-16T11:54:30","guid":{"rendered":"https:\/\/genedrivenetwork.org\/blog\/a-new-chapter-in-the-fight-against-mosquitoes-resistance-to-malaria-insecticides\/"},"modified":"2019-12-16T11:54:30","modified_gmt":"2019-12-16T11:54:30","slug":"a-new-chapter-in-the-fight-against-mosquitoes-resistance-to-malaria-insecticides","status":"publish","type":"post","link":"https:\/\/genedrivenetwork.org\/fr\/blog\/a-new-chapter-in-the-fight-against-mosquitoes-resistance-to-malaria-insecticides\/","title":{"rendered":"A new chapter in the fight against mosquitoes\u2019 resistance to malaria insecticides"},"content":{"rendered":"<p>Researchers from the <a href=\"https:\/\/www.lstmed.ac.uk\/\">Liverpool School of Tropical Medicine (LSTM)<\/a> have characterized three genes associated with Anopheles gambiae mosquitoes\u2019 resistance to insecticides used in malaria control. According to findings, overexpression of the three genes (Cyp6m2, Cyp6p3 and Gste2) leads to resistance to all major insecticide classes currently applied to combat the disease \u2013 pyrethroids, carbamates, organochlorines, and organophosphates. The overexpression of just one of these genes already confers resistance to representatives of at least one type of the insecticides listed.<\/p>\n<p>For the study, Dr. Adriana Adolfi and her team created genetically modified mosquitoes that overexpressed specific genes that were already previously detected by the group as potential causes of acquiring insecticide resistance. These mosquitoes can be used to test new insecticides that, once incorporated to bed nets and sprays, can potentially recover the effectiveness of these tools.<\/p>\n<p><!--more--><\/p>\n<p>Increasing resistance to drugs and insecticides is one of the significant challenges to eradicating malaria, as recently pointed out by the <a href=\"https:\/\/www.who.int\/malaria\/publications\/world-malaria-report-2019\/en\/\">WHO World Malaria Report 2019<\/a>. Scientists are racing against time to overcome mosquitoes\u2019 resistance and develop innovative solutions like gene drive that could potentialize the effects of and complement current control methods to fight vector-borne diseases. As the WHO noted, innovation is critical if we want to eradicate the disease by 2050.<\/p>\n<p>La <a href=\"https:\/\/www.pnas.org\/content\/early\/2019\/12\/03\/1914633116\">full study<\/a> is available at the journal Proceedings of the National Academy of Sciences (PNAS). More information is also available at <a href=\"https:\/\/phys.org\/news\/2019-12-scientists-marker-insecticide-resistance-malaria.html\">Phys.org<\/a>.<\/p>","protected":false},"excerpt":{"rendered":"<p>Researchers from the Liverpool School of Tropical Medicine (LSTM) have characterized three genes associated with Anopheles gambiae mosquitoes\u2019 resistance to insecticides used in malaria control. According to findings, overexpression of the three genes (Cyp6m2, Cyp6p3 and Gste2) leads to resistance to all major insecticide classes currently applied to combat the disease \u2013 pyrethroids, carbamates, organochlorines,&hellip;<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[816],"tags":[1019,1018,1021,820,825,989,1017,819,1022,1023,919,1016,1020],"post_series":[],"class_list":["post-1648","post","type-post","status-publish","format-standard","hentry","category-blog","tag-adriana-adolfi","tag-anopheles-gambiae-mosquitoes","tag-carbamates","tag-gene-drive","tag-gene-drive-network","tag-insecticides-resistance","tag-liverpool-school-of-tropical-medicine","tag-malaria","tag-organochlorines","tag-organophosphates","tag-outreach-network-for-gene-drive-research","tag-pyrethroids","tag-who-world-malaria-report-2019","entry","no-media"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>A new chapter in the fight against mosquitoes\u2019 resistance to malaria insecticides - Gene Drive Network<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/genedrivenetwork.org\/fr\/blog\/a-new-chapter-in-the-fight-against-mosquitoes-resistance-to-malaria-insecticides\/\" \/>\n<meta property=\"og:locale\" content=\"fr_CA\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A new chapter in the fight against mosquitoes\u2019 resistance to malaria insecticides - Gene Drive Network\" \/>\n<meta property=\"og:description\" content=\"Researchers from the Liverpool School of Tropical Medicine (LSTM) have characterized three genes associated with Anopheles gambiae mosquitoes\u2019 resistance to insecticides used in malaria control. According to findings, overexpression of the three genes (Cyp6m2, Cyp6p3 and Gste2) leads to resistance to all major insecticide classes currently applied to combat the disease \u2013 pyrethroids, carbamates, organochlorines,&hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/genedrivenetwork.org\/fr\/blog\/a-new-chapter-in-the-fight-against-mosquitoes-resistance-to-malaria-insecticides\/\" \/>\n<meta property=\"og:site_name\" content=\"Gene Drive Network\" \/>\n<meta property=\"article:published_time\" content=\"2019-12-16T11:54:30+00:00\" \/>\n<meta name=\"author\" content=\"Outreach Network\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Outreach Network\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimation du temps de lecture\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/genedrivenetwork.org\\\/blog\\\/a-new-chapter-in-the-fight-against-mosquitoes-resistance-to-malaria-insecticides\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/genedrivenetwork.org\\\/blog\\\/a-new-chapter-in-the-fight-against-mosquitoes-resistance-to-malaria-insecticides\\\/\"},\"author\":{\"name\":\"Outreach Network\",\"@id\":\"https:\\\/\\\/yellow-elephant-938991.hostingersite.com\\\/#\\\/schema\\\/person\\\/1d9c8d06344303a2f901b899fc832279\"},\"headline\":\"A new chapter in the fight against mosquitoes\u2019 resistance to malaria insecticides\",\"datePublished\":\"2019-12-16T11:54:30+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/genedrivenetwork.org\\\/blog\\\/a-new-chapter-in-the-fight-against-mosquitoes-resistance-to-malaria-insecticides\\\/\"},\"wordCount\":244,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/yellow-elephant-938991.hostingersite.com\\\/#organization\"},\"keywords\":[\"Adriana Adolfi\",\"Anopheles gambiae mosquitoes\",\"carbamates\",\"Gene Drive\",\"Gene Drive Network\",\"insecticides resistance\",\"Liverpool School of Tropical Medicine\",\"Malaria\",\"organochlorines\",\"organophosphates\",\"Outreach Network for Gene Drive Research\",\"pyrethroids\",\"WHO World Malaria Report 2019\"],\"articleSection\":[\"Blog\"],\"inLanguage\":\"fr-CA\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/genedrivenetwork.org\\\/blog\\\/a-new-chapter-in-the-fight-against-mosquitoes-resistance-to-malaria-insecticides\\\/\",\"url\":\"https:\\\/\\\/genedrivenetwork.org\\\/blog\\\/a-new-chapter-in-the-fight-against-mosquitoes-resistance-to-malaria-insecticides\\\/\",\"name\":\"A new chapter in the fight against mosquitoes\u2019 resistance to malaria insecticides - 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